Synthesis of Trans-3, 4-Dibenzyl-2-Oxo-Tetrahydrofuran: Advanced Study| Chapter 5 | Theory and Applications of Chemistry Vol. 4

Trans-3,4-dibenzyl-2-oxo-tetrahydrofuran (6) a substituted tetrahydrofuranoid lignan was synthesized in 70% yield via the Stobbe condensation between (1) benzaldehyde and (2) diethyl succinate. The structure was confirmed by the spectral data such as infra-red, proton magnetic resonance and mass spectrum. It has two similar but non equivalent aromatic groups which appeared at δ: 6.48 – 6.76 and 7.06-7.25 as multiplets.

Author(s) Details –

Prof. I. R. Jack
Department of Chemistry, Rivers State University of Science and Technology, P.M.B. 5080, Port Harcourt, Nigeria.

Dr. K. O. Orubite
Department of Chemistry, Rivers State University of Science and Technology, P.M.B. 5080, Port Harcourt, Nigeria.

View Book – http://bp.bookpi.org/index.php/bpi/catalog/book/149

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