Prevalence of Vaginal Candidiasis among Pregnant Women in Nnewi Town of Anambra State, Nigeria: A Recent Perspective | Chapter 13 | Theory and Applications of Microbiology and Biotechnology Vol. 3

Vaginal candidiasis (VC) is a common genital tract infection that affects mostly women especially the pregnant women leading to complications as abortions, premature birth, low birth weight among others. Vaginal specimens were collected from 300 pregnant women attending pre-natal visits in three selected hospitals in Nnewi, Anambra State, Nigeria using sterile swab sticks. Specimens were cultured in Sabouraud and blood agar media under sterile condition. All pregnant patients were considered throughout the period of the study, having obtained an informed consent from them. Chisquare analysis of data indicated that ninety patients were positive for candidiasis, a prevalence rate of 30.0%. Furthermore, pregnant women aged 26 to 30 recorded the highest prevalence (13.669; df = 5) that was statistically significant (p<0.05). The women who in their third trimester of pregnancy were mostly infected (6.163; df = 2) with infection status which was highly significant (p<0.05). The symptomatic and asymptomatic patients were uniformly infected with Candida hence, there was no significant difference between them (p>0.05). Further stratification of the pregnant women according to their parity revealed that Candida infection decreased with parity and was significantly higher in those in their first and second pregnancy (p<0.01). Consideration of the socio-economic status and occupation of the pregnant women showed no significant difference (p>0.05).  It was suggested that avoidance of predisposing factors, Vaginal Candidosis could resolve within a short period of time.

Author(s)  Detail
s

Professor Okonkwo, Nnaemeka Joe
Department of Crop Science and Horticulture, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria.

Umeanaeto, Pauline Ukamaka
Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria

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Obesity and Pregnancy: Saudi Arabian Experience | Chapter 10 | Current Trends in Medicine and Medical Research Vol. 5

Objective: To determine the effect of obesity on pregnancy compared to non-obese pregnant Saudi women.

Methodology: This is a prospective cohort research conducted over seven months in Jeddah Maternity and Children Hospital (MCH), Jeddah, Saudi Arabia. Sample included pregnant women with single fetus and cephalic presentation came to the booking clinic. Participants were classified into 5 groups depending on their BMI according to WHO criteria as underweight, normal weight, overweight, obese & morbidly obese. SPSS was used with p-value of< 0.05 to calculate statistical significance.

Results: The frequency of abortion, postdated pregnancy and Caesarean section were higher in obese women compared to non-obese women.

Conclusion: Obese women pregnancy is a high risk for pregnancy and labor complications. It is advisable to achieve normal BMI before conception.

Author(s) Details

Dr. Mohammad Othman
Department of Obstetrics and Gynecology, Faculty of Medicine, Al Baha University, Saudi Arabia.

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Prevalence of Urinary Tract Infection and Antibiotic Resistance Pattern in Pregnant Women, Najran Region, Saudi Arabia | Chapter 13 | Theory and Applications of Microbiology and Biotechnology Vol. 1

Urinary Tract Infection (UTI) is one of the commonest infectious disease in pregnancy, and in pregnancy we have very limited number of antibiotics to treat the UTI. This study was conducted on 151 patients who attended the gynecology clinic during the study period. Nineteen UTI proven cases of UTI were studied for prevalence of microorganism and sensitivity pattern against different antibiotics. Among the bacteria isolated, Escherichia coli (73.68%) and Staphylococcus aureus (10.52%) were the most prevalent Gram negative and Gram positive bacteria respectively. To know the resistance pattern of microorganism we used commercially available discs of different antibiotics. Gram negative bacteria showed more resistance as compared to Gram positive one. It is observed that the most effective antibiotic for Gram negative isolates is Ceftriaxone (87.5%), followed by Amoxicillin + Clavulanic acid (81.25%), Amikacin (75%), Cefuroxime (75%), Cefixime (68.75%) and Mezlocillin (62.5%). For the Gram positive bacteria, Ceftriaxone, Amikacin and Amoxicillin + Clavulanic acid were the most effective antimicrobials (100%). Multidrug resistance Gram negative bacteria were also tested for Extended-spectrum Beta Lactamase (ESBL), 35.71% of E. coli isolates were ESBL producer.

Author(s) Details

Dr. Ali Mohamed Alshabi
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

Dr. Majed Saeed Alshahrani
Department of Obstetics and Gyneocology, Faculty of Medicine, Najran University, Najran, Saudi Arabia.

Dr. Saad Ahmed Alkahtani
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

Mohammad Shabib Akhtar
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

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