“Black Ink” Sonographic Pattern as a Predictor for Invasive Papillary Thyroid Microcarcinoma: A Case Report | Chapter 01 | Emerging Research in Medical Sciences Vol. 2

Background: This study investigated the utility of the Sonographic pattern “Black Ink” with BRAF mutation testing of thyroid fine-needle aspiration cytology specimens for the risk papillary thyroid microcarcinoma (PTMC).

Case Presentation: We describe a case of a 41-year-old Caucasian woman affected by a ultrasonography “Black Ink” papillary thyroid microcarcinoma (PTMC) of the left lobe of the thyroid gland with very tiny size (Ø 0.4 cm). The characteristics, with the Diagnostic Imaging using Ultrasonography (US), Superb Micro-Vascular Imaging (SMI), fine-needle-aspiration cytology (FNAC) and mutation analysis are here discussed. There are more rare subtypes of thyroid cancer as papillary microcarcinoma “Black Ink” that even if small, are invasive and there is why the need to early diagnosis to avoid their aggressive behavior is needed. Nowadays, focusing on the size, the cut-off for non-occult tiny tumors has dropped to 0.3 cm. This value is of great relevance.

Conclusion: Ultrasonography, FNAC and BRAF molecular study have proven to be the most sensitive diagnostic combination for the early detection of thyroid cancer. Despite the size of this micro-lesion, the Black Ink ultrasonographic pattern associated with malignant cytology at FNAC represents an important biological risk factor and could still be a predictor of the PTMC and risk for neck lymph node metastases.

Author(s) Details

Ersilio Trapanese
Interventional Ultrasound of Breast Oncology Screening, ASL Salerno, Italy.

Basilio Angrisani
Department of Anatomical Pathology, Del Mare Hospital, ASL Naples, Italy.

Alberto Angrisani
Department of Biology, University of Naples Federico II, Monte Sant’ Angelo University Complex, Italy.

Ermanno D’Arco
Department of Endocrine Surgery, San Francesco d’Assisi Hospital, ASL Salerno, Italy.

Mariano Agrusta
Department of Endocrinology and Diabetology, Cava Amalfi Hospital, ASL Salerno, Italy.

Carmine De Bartolomeis
Department of Endocrine Surgery, Barbantini Private Hospital, Lucca, Italy.

Stefano Laudati
Department of Anatomical Pathology, Del Mare Hospital, ASL Naples, Italy.

Giulio Tarro
President Foundation T. & L. de Beaumont Bonelli for Cancer Research, Italy.
World Academy of Biomedical Technologies (WABT), UNESCO, Paris, France.

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Risk Factors for Developmental Dysplasia of The Hip | Chapter 02 | New Insights into Disease and Pathogen Research Vol. 2

Aims: To identify the association between potential risk factors with developmental dysplasia of the hip in neonates.

Study Design: A cross-sectional study.

Place and Duration of the Study: Laboratory of Lifestyle, Division of Health Sciences and Engineering, Campus Celaya Salvatierra, University of Guanajuato Mexico, between June 2014 and February 2015.

Methodology: We include 100 newborns, 36 male and 64 females with age between 4 and 28 days old. Data on birth weight, family history of hip dysplasia, obstetric presentation, mode of delivery, swaddling was obtained. The diagnosis of hip dysplasia hip ultrasonography with Graf technique was confirmed. For association Chi squared and p value, for the effect was calculated Odds Ratio and confidence intervals at 95%.

Results: It was found that obstetric presentation and swaddling were associated with developmental dysplasia of the hip (p <0.05) with OR of 5.32 and 4.91 respectively, and the association was confounded by area of residence with OR adjusted 2.94.

Conclusion: It was conclude that the most important risk factors for developmental dysplasia of the hip in this population were obstetric presentation and excessive swaddling.

Author(s) Details

Dr. Nicolas Padilla- Raygoza
School of Medicine, University of Celaya, Celaya,Mexico.

Silvia del Carmen Delgado-Sandoval
Department of Nursing and Obstetrics, Division of Health Sciences and Engineering, Campus Celaya-Salvatierra, University of Guanajuato, Celaya, Mexico.

María de Lourdes García-Campos
Department of Clinical Nursing, Division of Health Sciences and Engineering, Campus Celaya-Salvatierra, University of Guanajuato, Celaya, Mexico.

Carolina Mendoza-Lara
Division of Health Sciences and Engineering, Campus Celaya-Salvatierra, University of Guanajuato, Celaya, Mexico.

Georgina Olvera-Villanueva
Department of Nursing and Obstetrics, Division of Health Sciences and Engineering, Campus Celaya-Salvatierra, University of Guanajuato, Celaya, Mexico.

Verónica Benítez-Guerrero
Academic Unit of Nursing, Institute of Health Sciences, University Autonomous of Nayarit, Tepic, Celaya, Mexico.

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View Volume: https://doi.org/10.9734/bpi/nidpr/v2