Prevalence of Urinary Tract Infection and Antibiotic Resistance Pattern in Pregnant Women, Najran Region, Saudi Arabia | Chapter 13 | Theory and Applications of Microbiology and Biotechnology Vol. 1

Urinary Tract Infection (UTI) is one of the commonest infectious disease in pregnancy, and in pregnancy we have very limited number of antibiotics to treat the UTI. This study was conducted on 151 patients who attended the gynecology clinic during the study period. Nineteen UTI proven cases of UTI were studied for prevalence of microorganism and sensitivity pattern against different antibiotics. Among the bacteria isolated, Escherichia coli (73.68%) and Staphylococcus aureus (10.52%) were the most prevalent Gram negative and Gram positive bacteria respectively. To know the resistance pattern of microorganism we used commercially available discs of different antibiotics. Gram negative bacteria showed more resistance as compared to Gram positive one. It is observed that the most effective antibiotic for Gram negative isolates is Ceftriaxone (87.5%), followed by Amoxicillin + Clavulanic acid (81.25%), Amikacin (75%), Cefuroxime (75%), Cefixime (68.75%) and Mezlocillin (62.5%). For the Gram positive bacteria, Ceftriaxone, Amikacin and Amoxicillin + Clavulanic acid were the most effective antimicrobials (100%). Multidrug resistance Gram negative bacteria were also tested for Extended-spectrum Beta Lactamase (ESBL), 35.71% of E. coli isolates were ESBL producer.

Author(s) Details

Dr. Ali Mohamed Alshabi
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

Dr. Majed Saeed Alshahrani
Department of Obstetics and Gyneocology, Faculty of Medicine, Najran University, Najran, Saudi Arabia.

Dr. Saad Ahmed Alkahtani
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

Mohammad Shabib Akhtar
Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.

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The Role of Chromogenic Replica System for Isolation & Identification of Uropathogens in the Era of Molecular Diagnostics | Chapter 03 | New Insights into Disease and Pathogen Research Vol. 1

Multidrug resistance in uropathogens is a serious problem in a health care set up. To deal with that, rapid identification of the etiological agent from clinical urine sample is utmost important. Use of replica disc for presumptive identification of uropathogens is an easy to perform, cost effective and rapid method, which can be, adopted in the microbiology laboratories as a primary screening method.

Author(s) Details

Dr. Seema Bose

Department of Microbiology, Hind Institute of Medical Sciences, Safedabad, Lucknow, India.

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View Volume: https://doi.org/10.9734/bpi/nidpr/v1